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Medicinal Marine Life: Anti-Tubercular Compounds

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  • ISBN Number: 9789368643197
  • Author: Dr. Santhanam Ramesh, Dr. Ramasamy Santhanam, Dr. Veintramuthu Sankar
  • Binding: Hardcover
  • Publication Year: 2027
  • Pages: 193

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Overview

Tuberculosis (TB), caused by Mycobacterium tuberculosis (M. tb), continues to be a global health burden and it remains the leading cause of death from a single infectious agent after COVID-19. According to the WHO (2025), an estimated 1.25 million deaths were attributed to TB in 2024 alone. It is estimated that nearly one-quarter of the global population carries latent M. tb infection, and approximately 5–10% of these individuals will develop active TB during their lifetime. Multidrug-resistant tuberculosis (MDR-TB), characterized by resistance to the two most effective first-line drugs viz. isoniazid and rifampin;  and extensively drug-resistant tuberculosis (XDR-TB), which exhibits additional resistance to fluoroquinolones present a serious threat to global TB control efforts. This alarming trend underscores the urgent need for discovering novel anti-TB therapeutics with a new mechanism of action to overcome resistance.  Marine ecosystems offer vast scope in the development of new anti-tubercular drugs. Marine anti-tubercular compounds such as upenamide, aspyronol, and manzamine derivatives derived from sponges, bacteria, and algae can fight Mycobacterium tuberculosis. These ocean-based molecules offer new ways to treat drug-resistant strains of tuberculosis.

Though few books are presently available on the Medicinal Marine Life, no books have hither-to-been published on the anti-tubercular marine life. The present title when published would therefore be of great use for students and teachers of the disciplines such as Marine Biology, Fisheries Science, Life Sciences, and Pharmaceutical Sciences besides serving as a potent reference source and manual for drug industries in the development of new, marine-biota based anti-tubercular  drugs.

DR. RAMASAMY SANTHANAM

Dr. Ramasamy Santhanam is the former Dean of the Fisheries College and Research Institute, Tamil Nadu Veterinary and Animal Sciences University (presently under Tamil Nadu Dr. J. Jayalalithaa Fisheries University), Thoothukudi, TN, India. On invitation, he participated and presented research papers in 13 International Fisheries Science Conferences held at Canada, Japan, Panama, Denmark, Germany, Spain, The Netherlands, Switzerland, South Korea, and Australia. He has also served as a Resource Person for the Training Workshop organized by the Marine Science and Fisheries Centre, Ministry of Agriculture and Fisheries Wealth, Muscat, Oman. He was an active Member of the American Fisheries Society, United States; World Aquaculture Society, United States; Global Fisheries Ecosystem Management Network (GFEMN), United States; and the IUCN’s Commission on Ecosystem Management, Switzerland. To his credit, Dr. Santhanam has 50 books published on various aspects of Marine Biology/Fisheries Science; and three of his books have been listed as “Best Marine Biology Books of All Time” by the World Book Authority.

DR. SANTHANAM RAMESH

Dr. Santhanam Ramesh is presently serving as Vice-Principal, Karuna College of Pharmacy, Kerala University of Health Sciences, Palakkad, Kerala, India. He has 12 years of teaching and research experience. He was a Visiting Professor in the Medical Institute of the North- Caucasian State Humanitarian and Technological Academy (The state university), Cherkessk, Karachay-Cherkessia, Russia. He is an Associate Member of the Academic Pharmacy Group of Royal Pharmaceutical Society, London; Member of the International Society for Pharmacoeconomics and Outcome Research (ISPOR), USA; and Member of the British Society for Nanomedicine, U.K. To his credit, Dr. Ramesh has 19 books and 20 research papers

DR. VEINTRAMUTHU SANKAR

Dr. Veintramuthu Sankar is serving as Vice-Principal at P.S.G. College of Pharmacy, Coimbatore, TN, India. He has more than 20 years of teaching and research experience. He is an international expert of biopharmaceutics and pharmacokinetics; and on invitation, he has participated 4 international conferences held at Singapore, Malysia, and Hong Kong. He has also undergone advanced clinical training at Childrens’ Hospital of Eastern Ontario, Canada. He is the recipient of two Best Pharmacy Teacher Awards. Presently he is serving as the Editor of International Journal of Pharma Research; .and an active member of pharmacy bodies viz. IPA, APTI, IPGA and IHPA. To his credit, Dr. Sankar has one patent, two textbooks and more

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